mSphere of Influence: Experimental Evolution of RNA Viruses | Zendy

Gonzalo Moratorio | Zendy

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mSphere of Influence: Experimental Evolution of RNA Viruses

Author(s) -

Gonzalo Moratorio

Publication year - 2020

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.00179-20

Subject(s) - codon usage bias , experimental evolution , genome , biology , rna , robustness (evolution) , rna virus , virus , viral evolution , genetics , evolutionary biology , computational biology , gene

Gonzalo Moratorio works in the field of experimental evolution of viruses. In this mSphere of Influence article, he reflects on how the papers "Virus attenuation by genome-scale changes in codon pair bias" by Coleman et al. (Science 320:1784-1787, 2008, https://doi.org/10.1126/science.1155761) and "Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus" by Lauring et al. (Cell Host Microbe 12:623-632, 2012, https://doi.org/10.1016/j.chom.2012.10.008) made an impact on his thinking about how to employ synthetic biology to study experimental evolution of viruses.

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