Open AccessA Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the Candida Chlamydospore Cell Wall
Author(s) -
Leo D. Bemena,
Kyung-Hee Min,
James B. Konopka,
Aaron M. Neiman
Publication year - 2021
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00080-21
Subject(s) - chitin , cell wall , chitosan , saccharomyces cerevisiae , candida dubliniensis , chitin synthase , yeast , chlamydospore , s layer , biology , microbiology and biotechnology , hypha , chemistry , biochemistry , corpus albicans , gene , spore
The cell wall is the interface between the fungal cell and its environment and disruption of cell wall assembly is an effective strategy for antifungal therapies. Therefore, a detailed understanding of how cell walls form is critical to identify potential drug targets and develop therapeutic strategies.