Discovery of a Novel Bat Gammaherpesvirus | Zendy

Kurtis M. Host | Zendy; Blossom Damania | Zendy

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Discovery of a Novel Bat Gammaherpesvirus

Author(s) -

Kurtis M. Host,

Blossom Damania

Publication year - 2016

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.00016-16

Subject(s) - biology , virology , phylogenetic tree , zoonosis , virus , identification (biology) , genetics , gene , computational biology , botany

Zoonosis is the leading cause of emerging infectious diseases. In a recent article, R. S. Shabman et al. (mSphere 1[1]:e00070-15, 2016, http://dx.doi.org/10.1128/mSphere.00070-15) report the identification of a novel gammaherpesvirus in a cell line derived from the microbat Myotis velifer incautus. This is the first report on a replicating, infectious gammaherpesvirus from bats. The new virus is named bat gammaherpesvirus 8 (BGHV8), also known as Myotis gammaherpesvirus 8, and is able to infect multiple cell lines, including those of human origin. Using next-generation sequencing technology, the authors constructed a full-length annotated genomic map of BGHV8. Phylogenetic analysis of several genes from BGHV8 revealed similarity to several mammalian gammaherpesviruses, including Kaposi's sarcoma-associated herpesvirus (KSHV).

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