Whole-Genome Sequencing of a Brucella melitensis Strain (BMWS93) Isolated from a Bank Clerk and Exhibiting Complete Resistance to Rifampin
Author(s) -
Zhiguo Liu,
Xiaoan Cao,
Miao Wang,
Dongri Piao,
Hongyan Zhao,
Buyun Cui,
Hai Jiang,
Zhenjun Li
Publication year - 2019
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.01645-18
Subject(s) - brucella melitensis , whole genome sequencing , brucella , brucellosis , strain (injury) , microbiology and biotechnology , genome , inner mongolia , antibiotic resistance , biology , virology , china , genetics , gene , antibiotics , geography , archaeology , anatomy
Human brucellosis has become the most severe public health problem in the Ulanqab region of Inner Mongolia, China. Brucella melitensis BMWS93 was obtained from a blood sample taken from a bank clerk in the Ulanqab region of Inner Mongolia, China, and antimicrobial susceptibility testing in vitro showed no zone of inhibition, which confirmed resistance to rifampin. Therefore, whole-genome sequencing of this isolate was performed to better understand the mechanism of this resistance.
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