High-Depth RNA-Seq Data Sets for Studying Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae | Zendy

John M. Atack | Zendy; Lauren O. Bakaletz | Zendy; Michael P. Jennings | Zendy

Open Access

High-Depth RNA-Seq Data Sets for Studying Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae

Author(s) -

John M. Atack,

Lauren O. Bakaletz,

Michael P. Jennings

Publication year - 2019

Publication title -

microbiology resource announcements

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.383

H-Index - 35

ISSN - 2576-098X

DOI - 10.1128/mra.01500-18

Subject(s) - haemophilus influenzae , methyltransferase , gene , biology , rna , phase variation , pathogen , microbiology and biotechnology , dna , gene expression , genetics , virulence , antibiotics , methylation

Nontypeable Haemophilus influenzae (NTHi) is a major bacterial pathogen that causes multiple infections. We report high-depth-coverage RNA-Seq data from three NTHi strains, each of which encodes a different phase-variable methyltransferase. Major gene expression differences occur, commensurate with modA phase variation, and data will serve as an important resource for future studies.

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