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We report the complete genome sequence for Streptococcus pyogenes strain 1838 (type emm 3) isolated from a patient with toxic shock syndrome. The strain lacked the speK - and sla -encoding prophage frequently encountered among emm 3 strains and possessed an Arg66His mutation in CovR of the 2-component virulence regulatory system CovRS.

Complete Genome Sequence of Hypervirulent Streptococcus pyogenes emm 3 Strain 1838