Escherichia coli NGF-1, a Genetically Tractable, Efficiently Colonizing Murine Gut Isolate
Author(s) -
Marika Ziesack,
Michiel A. P. Karrenbelt,
Johannes Bues,
Elena Schaefer,
Pamela A. Silver,
Jeffrey C. Way
Publication year - 2018
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.01416-18
Subject(s) - escherichia coli , plasmid , biology , genetically modified organism , genome , chromosome , strain (injury) , genetically engineered , enterobacteriaceae , genetics , recombinant dna , microbiology and biotechnology , gene , anatomy
The genome of the murine commensal strain Escherichia coli NGF-1 contains a 5.03-Mbp chromosome and plasmids of 40.2 kbp and 8.56 kbp. NGF-1 efficiently colonizes the mouse gut and is genetically tractable. The genome sequence reported here facilitates genetic engineering and research in mouse models of healthy and diseased intestine.
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