Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate | Zendy

Travis J. Kochan | Zendy; Egon A. Ozer | Zendy; Nathan B. Pincus | Zendy; Margaret A. Fitzpatrick | Zendy; Alan R. Hauser | Zendy

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Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate

Author(s) -

Travis J. Kochan,

Egon A. Ozer,

Nathan B. Pincus,

Margaret A. Fitzpatrick,

Alan R. Hauser

Publication year - 2020

Publication title -

microbiology resource announcements

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.383

H-Index - 35

ISSN - 2576-098X

DOI - 10.1128/mra.01408-19

Subject(s) - klebsiella pneumoniae , plasmid , microbiology and biotechnology , whole genome sequencing , biology , bacteremia , gene , strain (injury) , genome , multiple drug resistance , klebsiella , genetics , drug resistance , antibiotics , escherichia coli , anatomy

Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra -associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.

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