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Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
Author(s) -
Travis J. Kochan,
Egon A. Ozer,
Nathan B. Pincus,
Margaret Fitzpatrick,
Alan R. Hauser
Publication year - 2020
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.01408-19
Subject(s) - klebsiella pneumoniae , plasmid , microbiology and biotechnology , whole genome sequencing , biology , bacteremia , gene , strain (injury) , genome , multiple drug resistance , klebsiella , genetics , drug resistance , antibiotics , escherichia coli , anatomy
Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra -associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.

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