Open AccessClosed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community
Author(s) -
Quentin Lamy-Besnier,
Romain Koszul,
Laurent Debarbieux,
Martial Marbouty
Publication year - 2021
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.01396-20
Subject(s) - genome , biology , genetics , bacterial artificial chromosome , chromosome , bacterial genome size , computational biology , gene
The Oligo-Mouse-Microbiota (OMM 12 ) gnotobiotic murine model is an increasingly popular model in microbiota studies. However, following Illumina and PacBio sequencing, the genomes of the 12 strains could not be closed. Here, we used genomic chromosome conformation capture (Hi-C) data to reorganize, close, and improve the quality of these 12 genomes.