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First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
Author(s) -
Aspen M. Workman,
Michael L. Clawson,
Michael P. Heaton,
Aaron M. Dickey
Publication year - 2018
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.01337-18
Subject(s) - lentivirus , biology , genotype , genetics , genome , frameshift mutation , gene , sequence (biology) , virology , mutation , whole genome sequencing , virus , viral disease
Genetic variation in the ovineTMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of aTMEM154 frameshift mutation predicted to abolish protein function.

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