Open AccessTranscriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
Author(s) -
John M. Atack,
Timothy F. Murphy,
Melinda M. Pettigrew,
Kate L. Seib,
Michael P. Jennings
Publication year - 2019
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.00526-19
Subject(s) - transcriptome , haemophilus influenzae , copd , gene , pulmonary disease , methyltransferase , biology , gene expression , microbiology and biotechnology , genetics , medicine , antibiotics , methylation
Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA phase variation results in gene expression differences. These data will serve as an important resource for future studies.