Near-Complete Genome Sequence of a Human Norovirus GII.1[Pg] Strain Associated with Acute Gastroenteritis, Determined Using Long-Read Sequencing | Zendy

Zhihui Yang | Zendy; Mark K. Mammel | Zendy; Samantha Q. Wales | Zendy

Open Access

Near-Complete Genome Sequence of a Human Norovirus GII.1[Pg] Strain Associated with Acute Gastroenteritis, Determined Using Long-Read Sequencing

Author(s) -

Zhihui Yang,

Mark K. Mammel,

Samantha Q. Wales

Publication year - 2021

Publication title -

microbiology resource announcements

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.383

H-Index - 35

ISSN - 2576-098X

DOI - 10.1128/mra.00401-21

Subject(s) - norovirus , acute gastroenteritis , whole genome sequencing , dna sequencing , biology , genome , computational biology , identification (biology) , virology , strain (injury) , genetics , gene , virus , botany , anatomy

High-throughput sequencing is one of the approaches used for the detection of foodborne pathogens such as noroviruses. Long-read sequencing has advantages over short-read sequencing in speed, read length, and lower fragmentation bias, which makes it a potential powerful tool for the fast detection and identification of viruses. Using Nanopore sequencing technology, we were able to successfully recover a nearly complete genome sequence of a human norovirus GII.1[Pg] strain in a single long read from a sample from a patient with norovirus gastroenteritis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research