Open AccessComplete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
Author(s) -
Gorata Modikwe,
Lokeshwaran Manoharan,
Gomolemo Mabutho,
Kebaneilwe Lebani,
Lesedi Lebogang,
Nerve Zhou
Publication year - 2021
Publication title -
microbiology resource announcements
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2576-098X
DOI - 10.1128/mra.00175-21
Subject(s) - antimicrobial , whole genome sequencing , genome , biology , gene , plasmid , antimicrobial drug , strain (injury) , antibiotic resistance , secondary metabolite , sequence (biology) , drug resistance , genetics , computational biology , microbiology and biotechnology , bacteria , anatomy
The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.