Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana | Zendy

Gorata Modikwe | Zendy; Lokeshwaran Manoharan | Zendy; Gomolemo Mabutho | Zendy; Kebaneilwe Lebani | Zendy; Lesedi Lebogang | Zendy; Nerve Zhou | Zendy

Open Access

Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana

Author(s) -

Gorata Modikwe,

Lokeshwaran Manoharan,

Gomolemo Mabutho,

Kebaneilwe Lebani,

Lesedi Lebogang,

Nerve Zhou

Publication year - 2021

Publication title -

microbiology resource announcements

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.383

H-Index - 35

ISSN - 2576-098X

DOI - 10.1128/mra.00175-21

Subject(s) - antimicrobial , whole genome sequencing , genome , biology , gene , plasmid , antimicrobial drug , strain (injury) , antibiotic resistance , secondary metabolite , sequence (biology) , drug resistance , genetics , computational biology , microbiology and biotechnology , bacteria , anatomy

The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

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