Fungal Recognition and Host Defense Mechanisms | Zendy

Ivy M. Dambuza | Zendy; Stuart M. Levitz | Zendy; Mihai G. Netea | Zendy; Gordon D. Brown | Zendy

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Fungal Recognition and Host Defense Mechanisms

Author(s) -

Ivy M. Dambuza,

Stuart M. Levitz,

Mihai G. Netea,

Gordon D. Brown

Publication year - 2017

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/microbiolspec.funk-0050-2016

Subject(s) - immune system , biology , host (biology) , pandemic , immunology , defence mechanisms , incidence (geometry) , ecology , covid-19 , medicine , disease , gene , genetics , pathology , physics , infectious disease (medical specialty) , optics

Fungi have emerged as premier opportunistic microbes of the 21st century, having a considerable impact on human morbidity and mortality. The huge increase in incidence of these diseases is largely due to the HIV pandemic and use of immunosuppressive therapies, underscoring the importance of the immune system in defense against fungi. This article will address how the mammalian immune system recognizes and mounts a defense against medically relevant fungal species.

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