Open AccessStructure of a murine alpha interferon pseudogene with a repetitive R-type sequence in the 3' flanking region.
Author(s) -
D Le Roscouet,
Guilane Vodjdani,
Y Lemaigre-Dubreuil,
M G Tovey,
M Latta,
Janine Doly
Publication year - 1985
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.5.6.1343
Subject(s) - pseudogene , biology , genetics , gene , nucleic acid sequence , alpha interferon , microbiology and biotechnology , 5' flanking region , peptide sequence , stop codon , oligonucleotide , sequence (biology) , interferon , gene expression , genome , promoter
A murine alpha interferon pseudogene was identified in a mouse genomic library. The nucleotide sequence revealed several in-phase termination codons within the gene and repetitive oligonucleotides in the flanking regions. The nucleotide sequences and the amino acids of the peptide signal sequences were compared with known human alpha interferon genes and the pseudogene.