Open AccessMurine cell complementation of a cold-sensitive defect for simian virus 40 replication in simian cells.
Author(s) -
L Fischer-Fantuzzi,
Cesare Vesco
Publication year - 1982
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.2.9.1155
Subject(s) - simian , biology , complementation , virology , virus , simian immunodeficiency virus , 3t3 cells , viral replication , cell culture , transfection , genetics , gene , phenotype
Mouse 3T3 fibroblasts were found to complement, in simian cell variants semipermissive to simian virus 40, a cold-sensitive defect of an early function, but not a nonconditional defect of viral uncoating. The variant simian cells could rescue simian virus 40 from 3T3 transformants, and this capacity was not temperature dependent.