Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus. | Zendy

Genoveffa Franchini | Zendy; Edward P. Gelmann | Zendy; Riccardo DallaFavera | Zendy; Robert C. Gallo | Zendy; Flossie WongStaal | Zendy

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Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus.

Author(s) -

Genoveffa Franchini,

Edward P. Gelmann,

Riccardo DallaFavera,

Robert C. Gallo,

Flossie WongStaal

Publication year - 1982

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.2.8.1014

Subject(s) - biology , gene , recombinant dna , genetics , homologous chromosome , virology , dna , locus (genetics) , microbiology and biotechnology , virus , sequence analysis

The onc gene (v-fes) of the acutely transforming feline sarcoma virus (Snyder-Theilen strain) has homologous cellular sequences (c-fes) in all vertebrate species, including humans. We isolated from a human DNA library recombinant phages containing overlapping c-fes sequences. The human c-fes locus spans a region of 3.4 kilobases and contains 1.4 kilobases of DNA homologous to the viral onc sequence interspersed with three intervening sequences.

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