The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway | Zendy

Azlann Arnett | Zendy; Keagan G. Moo | Zendy; Kaitlin J. Flynn | Zendy; Thomas B. Sundberg | Zendy; Liv Johannessen | Zendy; Alykhan F. Shamji | Zendy; Nathanael S. Gray | Zendy; Thomas Decker | Zendy; Ye Zheng | Zendy; Vivian H. Gersuk | Zendy; Ziaur S. M. Rahman | Zendy; David E. Levy | Zendy; Isabelle Marié | Zendy; Peter S. Linsley | Zendy; Ramnik J. Xavier | Zendy; Bernard Khor | Zendy

Open Access

The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4⁺ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway

Author(s) -

Azlann Arnett,

Keagan G. Moo,

Kaitlin J. Flynn,

Thomas B. Sundberg,

Liv Johannessen,

Alykhan F. Shamji,

Nathanael S. Gray,

Thomas Decker,

Ye Zheng,

Vivian H. Gersuk,

Ziaur S. M. Rahman,

David E. Levy,

Isabelle Marié,

Peter S. Linsley,

Ramnik J. Xavier,

Bernard Khor

Publication year - 2021

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00085-21

Subject(s) - biology , foxp3 , microbiology and biotechnology , cyclin dependent kinase 8 , immune system , acquired immune system , cellular differentiation , innate immune system , transcription factor , immunophenotyping , gata3 , kinase , signal transduction , immunology , genetics , flow cytometry , gene , notch signaling pathway

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