Open AccessTransition of Dephospho-DctD to the Transcriptionally Active State via Interaction with Dephospho-IIA Glc
Author(s) -
Sebin Kang,
Kyung-Jo Lee
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03839-21
Subject(s) - vibrio vulnificus , enhancer , mannose , phosphorylation , transcription factor , biochemistry , transcription (linguistics) , chemistry , pep group translocation , dna , gene expression , microbiology and biotechnology , gene , biology , bacteria , genetics , phosphoenolpyruvate carboxykinase , linguistics , philosophy
Transcription regulation by bacterial two-component systems is achieved by a response regulator upon its transition to the transcriptionally active form via kinase activity of its cognate sensor under specific conditions. A well-known response regulator, DctD, is converted to its phosphorylated form when DctB senses ambient dicarboxylic acids.