Open AccessNovel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles
Author(s) -
Yueyue Duan,
Liyan Cao,
Cong Yuan,
Xuepeng Suo,
Xiangyu Kong,
Yulong Gao,
Xiangtong Li,
Dan Li,
Xiaomei Wang,
Qi Wang
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03287-21
Subject(s) - biology , retrovirus , histone , viral replication , rous sarcoma virus , virology , viremia , acetylation , virus , carcinogenesis , histone deacetylase , replication timing , microbiology and biotechnology , dna replication , gene , genetics
Rous sarcoma virus (RSV)/ALV was the first retrovirus to be discovered, which was really the first hint that cancer, or a tumor, could be transmitted by a virus. The specific mechanisms that regulate ALV replication during infection remain poorly understood.