Open AccessRotavirus NSP1 Contributes to Intestinal Viral Replication, Pathogenesis, and Transmission
Author(s) -
Gaopeng Hou,
Qiru Zeng,
Jelle Matthijnssens,
Harry B. Greenberg,
Siyuan Ding
Publication year - 2021
Publication title -
mbio
Language(s) - English
Resource type - Journals
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03208-21
Subject(s) - virology , transmission (telecommunications) , rotavirus , pathogenesis , replication (statistics) , viral replication , viral pathogenesis , biology , microbiology and biotechnology , medicine , virus , immunology , computer science , telecommunications
Rotavirus remains one of the most important causes of severe diarrhea and dehydration in young children worldwide. Although NSP1 is dispensable for rotavirus replication in cell culture, its exact role in virus infectionin vivo remains unclear.
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