Open AccessGenomic Drivers of Multidrug-Resistant Shigella Affecting Vulnerable Patient Populations in the United States and Abroad
Author(s) -
Jay N. Worley,
Kiran Javkar,
Maria Hoffmann,
Kristen Hysell,
Amanda Garcia-Williams,
Kaitlin A. Tagg,
Sanjat Kanjilal,
Errol Strain,
Mihai Pop,
Marc W. Allard,
Louise Francois Watkins,
Lynn Bry
Publication year - 2021
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03188-20
Subject(s) - outbreak , shigella , multiple drug resistance , transmission (telecommunications) , shigellosis , public health , pathogen , biology , environmental health , medicine , microbiology and biotechnology , virology , drug resistance , genetics , salmonella , bacteria , telecommunications , nursing , computer science
Multidrug-resistantShigella isolates with resistance to macrolides are an emerging public health threat. We define a plasmid/pathogen complex behind infections seen in the United States and globally in vulnerable patient populations and identify multiple outbreaks in the United States and evidence of intercontinental transmission.