Open AccessDirect Intracellular Visualization of Ebola Virus-Receptor Interaction by In Situ Proximity Ligation
Author(s) -
Eva Mittler,
Tanwee Alkutkar,
Rohit K. Jangra,
Kartik Chandran
Publication year - 2021
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03100-20
Subject(s) - ebola virus , outbreak , ebolavirus , virology , disease , psychological intervention , medicine , geography , pathology , psychiatry
Ebola virus causes episodic but increasingly frequent outbreaks of severe disease in Middle Africa, as shown by the recently overcome second largest outbreak on record in the Democratic Republic of Congo. Despite considerable effort, FDA-approved antifiloviral therapeutics or targeted interventions are not available yet.