Open AccessStructural Characterization of Diazabicyclooctane β-Lactam “Enhancers” in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa
Author(s) -
Malligarjunan Rajavel,
Vijay Kumar,
Ha Son Nguyen,
Jacob Wyatt,
Steven H. Marshall,
Krisztina M. Papp-Wallace,
P. K. Deshpande,
Satish Bhavsar,
Ravindra Yeole,
Sachin Bhagwat,
Mahesh Patel,
Robert A. Bonomo,
F. van den Akker
Publication year - 2021
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03058-20
Subject(s) - penicillin binding proteins , pseudomonas aeruginosa , chemistry , microbiology and biotechnology , escherichia coli , biochemistry , biology , bacteria , gene , genetics
Antibiotic resistance is a significant clinical problem. Developing novel antibiotics that overcome known resistance mechanisms is highly desired.