Open AccessPoles Apart: Where and How Cells Construct Nisin
Author(s) -
Colin Hill
Publication year - 2020
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.02991-20
Subject(s) - nisin , lantibiotics , lactococcus lactis , operon , bacteriocin , microbiology and biotechnology , food preservatives , chemistry , biology , bacteria , computational biology , gene , biochemistry , genetics , lactic acid , antimicrobial , escherichia coli
Nisin is a 34-amino-acid lantibiotic that has been used commercially for almost a century as a food preservative. In order to produce active nisin, Lactococcus lactis requires an 11-gene operon that encodes proteins involved in modification, processing, transport, immunity, and regulation.