Open AccessStructure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein
Author(s) -
Trevor T. Dean,
Vitor Hugo Balasco Serrão,
Jeffrey E. Lee
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.02920-21
Subject(s) - biology , endogenous retrovirus , ectodomain , viral envelope , virology , viral entry , fusion protein , viral protein , retrovirus , lipid bilayer fusion , glycoprotein , viral evolution , microbiology and biotechnology , herpesvirus glycoprotein b , virus , genetics , computational biology , genome , viral replication , recombinant dna , gene , receptor
Class I viral fusion proteins represent a diverse group of fusogens that catalyze membrane fusion. Although structural studies have focused on those from exogenous viruses, ancient retroviral infections of germ line cells have immortalized ancient fusogens in eukaryotic genomes.