Open AccessMultivalent Interactions Drive the Toxoplasma AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap
Author(s) -
Peter Back,
William O’Shaughnessy,
Andy S Moon,
Pravin S Dewangan,
Michael L. Reese,
Peter J. Bradley
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.02864-21
Subject(s) - biology , cytoskeleton , organelle , microbiology and biotechnology , microneme , apical membrane , apicomplexa , intracellular , biochemistry , plasmodium falciparum , immunology , cell , membrane , malaria
The phylum Apicomplexa consists of obligate, intracellular parasites, including the causative agents of toxoplasmosis, malaria, and cryptosporidiosis. Hallmarks of these parasites are the IMC and the apical complex, both of which are unique structures that are conserved throughout the phylum and required for parasite survival.