A Bumpy Pathway to Stationary-Phase Survival in Bacillus subtilis | Zendy

Wayne L. Nicholson | Zendy

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A Bumpy Pathway to Stationary-Phase Survival in Bacillus subtilis

Author(s) -

Wayne L. Nicholson

Publication year - 2019

Publication title -

mbio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.562

H-Index - 121

eISSN - 2161-2129

pISSN - 2150-7511

DOI - 10.1128/mbio.02461-19

Subject(s) - bacillus subtilis , spore , stationary phase , microbiology and biotechnology , biology , bacteria , chemistry , genetics , chromatography

Bacillus subtilis cells can mount a number of responses to nutritional deprivation but ultimately either form dormant spores or enter a metabolically quiescent state. In a recent article (mBio 10:e01414-19, https://doi.org/10.1128/mBio.01414-19, 2019), R. Hashuel and S. Ben-Yehuda report on a novel means by which nutrient-starved B. subtilis cells escape from aging (days-old) colonies by accumulating mutations enabling them to continue growth under nutrient-limited conditions. They postulate that such a strategy may be a major factor determining the dynamics of bacterial populations in natural environments.

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