Intracellular Staphylococcus aureus Perturbs the Host Cell Ca 2+ Homeostasis To Promote Cell Death | Zendy

Kathrin Stelzner | Zendy; Ann-Cathrin Winkler | Zendy; Chunguang Liang | Zendy; Aziza Boyny | Zendy; Carsten P. Ade | Zendy; Thomas Dandekar | Zendy; Martin Fraunholz | Zendy; Thomas Rudel | Zendy

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Intracellular Staphylococcus aureus Perturbs the Host Cell Ca ²⁺ Homeostasis To Promote Cell Death

Author(s) -

Kathrin Stelzner,

Ann-Cathrin Winkler,

Chunguang Liang,

Aziza Boyny,

Carsten P. Ade,

Thomas Dandekar,

Martin Fraunholz,

Thomas Rudel

Publication year - 2020

Publication title -

mbio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.562

H-Index - 121

eISSN - 2161-2129

pISSN - 2150-7511

DOI - 10.1128/mbio.02250-20

Subject(s) - intracellular , staphylococcus aureus , homeostasis , microbiology and biotechnology , cell , chemistry , host (biology) , programmed cell death , bacteria , biology , biochemistry , apoptosis , genetics

Despite being regarded as an extracellular bacterium, the pathogen Staphylococcus aureus can invade and survive within human cells. The intracellular niche is considered a hideout from the host immune system and antibiotic treatment and allows bacterial proliferation.

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