Bacterial Metal Resistance: Coping with Copper without Cooperativity? | Zendy

Nicholas P. Greene | Zendy; Vassilis Koronakis | Zendy

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Bacterial Metal Resistance: Coping with Copper without Cooperativity?

Author(s) -

Nicholas P. Greene,

Vassilis Koronakis

Publication year - 2021

Publication title -

mbio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.562

H-Index - 121

eISSN - 2161-2129

pISSN - 2150-7511

DOI - 10.1128/mbio.00653-21

Subject(s) - efflux , transporter , escherichia coli , bacteria , bacterial cell structure , copper , trimer , chemistry , microbiology and biotechnology , biophysics , cell envelope , biology , biochemistry , dimer , gene , genetics , organic chemistry

InEscherichia coli and other Gram-negative bacteria, tripartite efflux pumps (TEPs) span the entire cell envelope and serve to remove noxious molecules from the cell. CusBCA is a TEP responsible for copper and silver detoxification inE. coli powered by the resistance-nodulation-cell division (RND) transporter, CusA.

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