
Genome-Wide Association Study of Campylobacter - Positive Diarrhea Identifies Genes Involved in Toxin Processing and Inflammatory Response
Author(s) -
Rebecca M. Munday,
Rashidul Haque,
J O H N,
Genevieve L. Wojcik,
Chelsea Marie,
Dylan Duchen,
Alexander J. Mentzer,
Uma Nayak,
Poonum Korpe,
Beth D. Kirkpatrick,
William A. Petri,
Priya Duggal
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.00556-22
Subject(s) - diarrhea , campylobacter , underweight , biology , inflammatory response , gut flora , toxin , genome wide association study , medicine , gene , microbiology and biotechnology , immunology , genetics , genotype , inflammation , bacteria , obesity , single nucleotide polymorphism , endocrinology , overweight
Children in low-to-middle-income countries often suffer from multiple enteric infections in their first few years of life, many of which have the potential for long-lasting effects. These children are already likely to be malnourished and underweight, and chronic intestinal disturbances exacerbate these conditions.