Open AccessInduction of Susceptibility to Disseminated Infection with IgA1 Protease-Producing Encapsulated Pathogens Streptococcus pneumoniae, Haemophilus influenzae Type b, and Neisseria meningitidis
Author(s) -
Mogens Kilian,
Steffen Husby,
Jesper Rye Andersen,
Zina Moldoveanu,
Uffe B. Skov Sørensen,
Jesper Reinholdt,
Hervé Tettelin
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.00550-22
Subject(s) - neisseria meningitidis , microbiology and biotechnology , streptococcus pneumoniae , haemophilus influenzae , pathogen , biology , protease , virology , bacterial capsule , proteases , neisseria , vaccination , immunology , bacteria , virulence , antibiotics , enzyme , biochemistry , genetics , gene
Why some individuals develop invasive infection, including meningitis, withStreptococcus pneumoniae ,Neisseria meningitidis , andHaemophilus influenzae type b is unexplained. The vast majority of humans are colonized with the three pathogens but remain healthy and develop immunity.