Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein
Author(s) -
Mizuki Yamamoto,
Jin Gohda,
Ayako Kobayashi,
Keiko Tomita,
Youko Hirayama,
Naohiko Koshikawa,
Motoharu Seiki,
Kentaro Semba,
Tetsu Akiyama,
Yasushi Kawaguchi,
Junichiro Inoue
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.00519-22
Subject(s) - furin , proteases , metalloproteinase , cleavage (geology) , tmprss2 , spike protein , covid-19 , receptor , microbiology and biotechnology , protease , cell , coronavirus , matrix metalloproteinase , spike (software development) , surface protein , chemistry , hek 293 cells , virology , biology , biochemistry , enzyme , computer science , medicine , disease , pathology , infectious disease (medical specialty) , paleontology , software engineering , fracture (geology)
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