Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus | Zendy

Michael P. Doyle | Zendy; Joseph Genualdi | Zendy; Adam L. Bailey | Zendy; Nurgun Kose | Zendy; Christopher Gainza | Zendy; Jessica Rodríguez | Zendy; Kristen M. Reeder | Zendy; Christopher A. Nelson | Zendy; Prashant N. Jethva | Zendy; Rachel E. Sutton | Zendy; Robin G. Bombardi | Zendy; Michael L. Gross | Zendy; Justin G. Julander | Zendy; Daved H. Fremont | Zendy; Michael Diamond | Zendy; James E. Crowe | Zendy

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Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus

Author(s) -

Michael P. Doyle,

Joseph Genualdi,

Adam L. Bailey,

Nurgun Kose,

Christopher Gainza,

Jessica Rodríguez,

Kristen M. Reeder,

Christopher A. Nelson,

Prashant N. Jethva,

Rachel E. Sutton,

Robin G. Bombardi,

Michael L. Gross,

Justin G. Julander,

Daved H. Fremont,

Michael Diamond,

James E. Crowe

Publication year - 2022

Publication title -

mbio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.562

H-Index - 121

eISSN - 2161-2129

pISSN - 2150-7511

DOI - 10.1128/mbio.00512-22

Subject(s) - virology , isolation (microbiology) , monoclonal antibody , virus , neutralizing antibody , antibody , yellow fever , biology , medicine , immunology , microbiology and biotechnology

Yellow fever virus (YFV) is a mosquito-borne virus that occasionally causes outbreaks of severe infection and disease in South America and sub-Saharan Africa. There are very effective live-attenuated (weakened) yellow fever virus vaccines, but recent problems with their production and distribution have left many people in affected areas vulnerable.

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