Open AccessAccessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX
Author(s) -
William C Shropshire,
An Q Dinh,
Michelle Earley,
Lauren Komarow,
Diana Panesso,
Kirsten Rydell,
Sara I Gómez-Villegas,
Hongyu Miao,
Carol Hill,
Liang Chen,
Robin Patel,
Bettina C. Fries,
Lilian M. Abbo,
Eric Cober,
Sara Revolinski,
Courtney Luterbach,
Henry F. Chambers,
Vance G. Fowler,
Robert A. Bonomo,
Samuel A. Shelburne,
Barry N. Kreiswirth,
David van Duin,
Blake Hanson,
César A. Arias
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.00497-22
Subject(s) - klebsiella pneumoniae , carriage , microbiology and biotechnology , carbapenem , biology , klebsiella , antimicrobial , klebsiella infections , medicine , virology , genetics , gene , escherichia coli , antibiotics , pathology
The prevalence of carbapenem-resistantKlebsiella pneumoniae (CRKp ) infections in nosocomial settings remains a public health challenge. High-risk clones such as clonal group 258 (CG258) are particularly concerning due to their association withbla KPC carriage, which can severely complicate antimicrobial treatments.