A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress | Zendy

Brian M. Wendel | Zendy; Hualiang Pi | Zendy; Larissa Krüger | Zendy; Christina Herzberg | Zendy; Jörg Stülke | Zendy; John D. Helmann | Zendy

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A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress

Author(s) -

Brian M. Wendel,

Hualiang Pi,

Larissa Krüger,

Christina Herzberg,

Jörg Stülke,

John D. Helmann

Publication year - 2022

Publication title -

mbio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.562

H-Index - 121

eISSN - 2161-2129

pISSN - 2150-7511

DOI - 10.1128/mbio.00092-22

Subject(s) - osmotic shock , homeostasis , osmotic concentration , chemistry , cytosol , limiting , potassium , osmotic pressure , magnesium , dehydration , biophysics , osmosis , biocompatible material , biochemistry , microbiology and biotechnology , biology , enzyme , membrane , medicine , organic chemistry , gene , mechanical engineering , engineering , biomedical engineering

Environments with high concentrations of salt or other solutes impose an osmotic stress on cells, ultimately limiting viability by dehydration of the cytosol. A very common cellular response to high osmolarity is to immediately import high levels of potassium ion (K+ ), which helps prevent dehydration and allows time for the import or synthesis of biocompatible solutes that allow a resumption of growth.

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