Open AccessLeukemogenic activity of thymotropic, ecotropic, and xenotropic radiation leukemia virus isolates
Author(s) -
Martin Haas
Publication year - 1978
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.25.3.705-709.1978
Subject(s) - biology , virology , leukemia , virus , oncovirus , inoculation , immunology
Thymotropic, ecotropic, and xenotropic oncoviruses were isolated from the C57BL/6 mouse radiation leukemia system and were propagated in culture. The purified viruses were inoculated singly and in various combinations into groups of mice, and leukemia incidence was determined. Only the thymotropic virus was leukemogenic in vivo.
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