
The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection
Author(s) -
Birthe Reinecke,
Nicola Frericks,
Chris Lauber,
Katja Dinkelborg,
Alina Matthaei,
Florian W. R. Vondran,
Patrick Behrendt,
Sibylle Haid,
Richard J. P. Brown,
Thomas Pietschmann
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01995-21
Subject(s) - biology , virology , hepatitis c virus , virus , ectopic expression , gene , genetics
The liver represents an immunoprivileged organ characterized by enhanced resistance to immune responses. However, the importance of liver cell-endogenous, noncytolytic innate immune responses in pathogen control is not well defined.