Open AccessAre COVID-19 Vaccine Boosters Needed? The Science behind Boosters
Author(s) -
Rachel M. Burckhardt,
John J. Dennehy,
Leo L. M. Poon,
Linda J. Saif,
Lynn W. Enquist
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01973-21
Subject(s) - herd immunity , pandemic , booster (rocketry) , covid-19 , virology , immunity , biology , immunology , vaccination , medicine , infectious disease (medical specialty) , immune system , disease , outbreak , physics , astronomy
Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown.