Open AccessThe A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1
Author(s) -
Mengling Sun,
Shaoxiong Yu,
Heng Ge,
Tao Wang,
Yongfeng Li,
Pingping Zhou,
Li Pan,
Yoo Min Han,
Yuying Yang,
Yuan Sun,
Su Li,
Lian-Feng Li,
HuaJi Qiu
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01957-21
Subject(s) - african swine fever virus , biology , virulence , virology , interferon , tank binding kinase 1 , virus , gene , autophagy , microbiology and biotechnology , genetics , apoptosis , cell cycle , cyclin dependent kinase 2
African swine fever (ASF) is a lethal viral disease of pigs caused by African swine fever virus (ASFV). No commercial vaccines and antiviral treatments are available for the prevention and control of the disease.