Open AccessTracking the Replication-Competent Zika Virus with Tetracysteine-Tagged Capsid Protein in Living Cells
Author(s) -
Shimin Li,
Dianbing Wang,
Ghulam Abbas,
Xia Li,
Min Li,
Qin Li,
Yingxin Ma,
Lei Wang,
Hangshen Wu,
Zongqiang Cui,
Xian-En Zhang
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01846-21
Subject(s) - zika virus , biology , capsid , virology , microcephaly , viral replication , flavivirus , virus , genetics
Zika virus (ZIKV) is the mosquito-borne enveloped flavivirus that causes microcephaly in neonates. While real-time imaging plays a critical role in dissecting viral biology, no fluorescent, genetically engineered ZIKV for single-particle tracking is currently available.