Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection | Zendy

Toshitada Takemori | Zendy; Akiko Sugimoto-Ishige | Zendy; Hironori Nishitsuji | Zendy; Yushi Futamura | Zendy; Michishige Harada | Zendy; Tomomi KimuraSomeya | Zendy; Takehisa Matsumoto | Zendy; Teruki Honma | Zendy; Miho Tanaka | Zendy; Masami Yaguchi | Zendy; Kyoichi Isono | Zendy; Haruhiko Koseki | Zendy; Hiroyuki Osada | Zendy; Daiki Miki | Zendy; Takashi Saito | Zendy; Takashi Tanaka | Zendy; Takehiro Fukami | Zendy; Toshio Goto | Zendy; Mikako Shirouzu | Zendy; Kunitada Shimotohno | Zendy; Kazuaki Chayama | Zendy

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Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection

Author(s) -

Toshitada Takemori,

Akiko Sugimoto-Ishige,

Hironori Nishitsuji,

Yushi Futamura,

Michishige Harada,

Tomomi KimuraSomeya,

Takehisa Matsumoto,

Teruki Honma,

Miho Tanaka,

Masami Yaguchi,

Kyoichi Isono,

Haruhiko Koseki,

Hiroyuki Osada,

Daiki Miki,

Takashi Saito,

Takashi Tanaka,

Takehiro Fukami,

Toshio Goto,

Mikako Shirouzu,

Kunitada Shimotohno,

Kazuaki Chayama

Publication year - 2022

Publication title -

journal of virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.617

H-Index - 292

eISSN - 1070-6321

pISSN - 0022-538X

DOI - 10.1128/jvi.01686-21

Subject(s) - biology , virology , monoclonal antibody , hepatitis b virus , antibody , hepatitis b , virus , immunology

A number of entry inhibitors are being developed to enhance the treatment of HBV patients with oral nucleoside/nucleotide analogues (NA). To amplify the effectiveness of NA therapy, several efforts have been made to develop therapeutic MAbs with neutralizing activity against HBs antigens.

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