Open AccessStructures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells
Author(s) -
Lena Ricemeyer,
Nayeli Aguilar-Hernández,
Tomás López,
Rafaela Espinosa,
Sarah Lanning,
Santanu Mukherjee,
Carolina Cuellar,
Susana López,
Rebecca M. DuBois
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01415-21
Subject(s) - astrovirus , capsid , virology , biology , epitope , antibody , virus , monoclonal antibody , neutralizing antibody , immunology , norovirus
Human astroviruses infect nearly every person in the world during childhood and cause diarrhea, vomiting, and fever. Despite the prevalence of this virus, little is known about how antibodies block astrovirus infection.