Open AccessNovel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research
Author(s) -
Leo Holguin,
Liliana Echavarria,
John Burnett
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01394-21
Subject(s) - viremia , peripheral blood mononuclear cell , humanized mouse , immunology , biology , immune system , graft versus host disease , antibody , stem cell , biochemistry , genetics , in vitro
Currently, there is no cure or vaccine for HIV infection; thus, continued research is needed to end the HIV pandemic. While many animal models are used in HIV research, none is used more than the humanized mouse model.