Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research | Zendy

Leo Holguin | Zendy; Liliana Echavarria | Zendy; John Burnett | Zendy

Open Access

Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research

Author(s) -

Leo Holguin,

Liliana Echavarria,

John Burnett

Publication year - 2021

Publication title -

journal of virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.617

H-Index - 292

eISSN - 1070-6321

pISSN - 0022-538X

DOI - 10.1128/jvi.01394-21

Subject(s) - humanized mouse , biology , peripheral blood mononuclear cell , virology , immunology , human immunodeficiency virus (hiv) , pandemic , disease , covid-19 , infectious disease (medical specialty) , immune system , medicine , pathology , genetics , in vitro

Currently, there is no cure or vaccine for HIV infection; thus, continued research is needed to end the HIV pandemic. While many animal models are used in HIV research, none is used more than the humanized mouse model.

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