Open AccessRole of E6 in Maintaining the Basal Cell Reservoir during Productive Papillomavirus Infection
Author(s) -
Taylor Saunders-Wood,
Nagayasu Egawa,
Ke Zheng,
Alberto Giaretta,
Heather Griffin,
John Doorbar
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01181-21
Subject(s) - biology , recurrent respiratory papillomatosis , human papillomavirus , hpv infection , papillomaviridae , virology , immunology , medicine , cervical cancer , cancer , genetics , larynx , anatomy
Persistent infection with high-risk HPV types can lead to development of HPV-associated cancers, and persistent low-risk HPV infection causes problematic diseases, such as recurrent respiratory papillomatosis. The management and treatment of these conditions pose a considerable economic burden.