The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus
Author(s) -
Wenjuan Dong,
Heather Mead,
Lei Tian,
JunGyu Park,
Juan Ignacio García,
Sierra A. Jaramillo,
Tasha Barr,
Daniel S. Kollath,
Vanessa K. Coyne,
Nathan E. Stone,
Ashley Jones,
Jianying Zhang,
Aimin Li,
LiShu Wang,
Martha MilanesYearsley,
Jordi B. Torrelles,
Luis MartínezSobrido,
Paul Keim,
Bridget M. Barker,
Michael A. Caligiuri,
Jianhua Yu
Publication year - 2021
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.00964-21
Subject(s) - biology , virus , virology , infectious dose , lung , genetically modified mouse , coronavirus , transgene , nasal administration , covid-19 , immunology , infectious disease (medical specialty) , pathology , disease , medicine , gene , biochemistry
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