Complementary Roles of Antibody Heavy and Light Chain Somatic Hypermutation in Conferring Breadth and Potency to the HIV-1-Specific CAP256-VRC26 bNAb Lineage
Author(s) -
David Sacks,
Kevin Wiehe,
Lynn Morris,
Penny L. Moore
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.00270-22
Subject(s) - biology , somatic hypermutation , potency , immunoglobulin light chain , paratope , complementarity determining region , neutralization , antibody , virology , lineage (genetic) , hiv vaccine , hypervariable region , genetics , gene , b cell , epitope , in vitro , vaccine trial
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