Machupo Virus with Mutations in the Transmembrane Domain and Glycosylation Sites of the Glycoprotein Is Attenuated and Immunogenic in Animal Models of Bolivian Hemorrhagic Fever
Author(s) -
Emily Mantlo,
Junki Maruyama,
John T. Manning,
Timothy G. Wanninger,
Cheng Huang,
Jea N. Smith,
Michael Patterson,
Slobodan Paessler,
Takaaki Koma
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.00209-22
Subject(s) - biology , virology , virulence , glycoprotein , attenuated vaccine , glycan , glycosylation , junin virus , transmembrane domain , transmembrane protein , microbiology and biotechnology , immunology , genetics , gene , antigen , lymphocytic choriomeningitis , cd8 , receptor
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