Open AccessReappraising the Value of HIV-1 Vaccine Correlates of Protection Analyses
Author(s) -
Per Johan Klasse,
John P. Moore
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.00034-22
Subject(s) - biology , vaccine efficacy , human immunodeficiency virus (hiv) , hiv vaccine , virology , vaccine trial , aids vaccines , immunology , vaccination
With the much-debated exception of the modestly reduced acquisition reported for the RV144 efficacy trial, HIV-1 vaccines have not protected humans against infection, and a vaccine of similar design to that tested in RV144 was not protective in a later trial, HVTN 702.