Open AccessSensitivity of the Multispot HIV-1/HIV-2 Rapid Test Using Samples from Human Immunodeficiency Virus Type 1-Positive Individuals with Various Levels of Exposure to Highly Active Antiretroviral Therapy
Author(s) -
Robert J. O’Connell,
Brian K. Agan,
Stephanie A. Anderson,
Jennifer Malia,
Nelson L. Michael
Publication year - 2006
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.44.5.1831-1833.2006
Subject(s) - virology , serostatus , human immunodeficiency virus (hiv) , medicine , population , viral disease , lentivirus , antiretroviral therapy , sida , antibody , immunology , biology , viral load , environmental health
The Multispot HIV-1/HIV-2 rapid test detects human immunodeficiency virus type 1 (HIV-1) gp41 antibodies, which can wane over time in some HIV-1-infected populations, resulting in false-negative screening results. Multispot sensitivity was 100% using 248 sera from one such population, and it correctly identified serostatus in individuals who previously tested false negative with rapid testing.